Wogonoside inhibits invasion and migration through suppressing TRAF2/4 expression in breast cancer
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چکیده
منابع مشابه
Wogonoside inhibits invasion and migration through suppressing TRAF2/4 expression in breast cancer
BACKGROUND Twist1 is involved in tumor initiation and progression, which especially contributes to tumor invasion and metastasis. Wogonoside is the main in-vivo metabolite of wogonin, and it is also a natural product with potential treatment effects against cancer. METHODS In this study, we investigated the in-vitro anti-invasion and in-vivo anti-metastasis effects of wogonoside on breast can...
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Wogonoside, a main flavonoid component derived from the root of Scutellaria baicalensis Georgi, has been reported to have anti-angiogenesis and anti-leukemia activities. However, whether it can inhibit tumor angiogenesis is unclear. In this study, we investigate the inhibitory effect of wogonoside on angiogenesis in breast cancer and its underlying mechanisms. ELISA assay shows that wogonoside ...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2017
ISSN: 1756-9966
DOI: 10.1186/s13046-017-0574-5